The Power of Intelligent SNP Selection
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چکیده
Every single nucleotide polymorphism (SNP) marker on Illumina Infinium® DNA Analysis BeadChips has been selected by Illumina scientists based on the high information content and genomic coverage it provides. Employing rationally selected SNPs rather than randomly chosen SNPs greatly improves the power to detect association and drastically reduces the number of samples required for successful genome-wide association studies (GWAS). This technical note explores this impact of array power on study efficiency.
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